While trying to evade the pursuing Soul Reapers and rescue Rukia, Orihime and Uryu are confronted by the captain of Squad 12, the despicable Mayuri Kurotsuchi, who plans on using them as guinea pigs for his experiments! Meanwhile, Yoruichi has revealed her true form to the astonishment of Ichigo and the others, and must use all her tricks and skills to keep her fellow intruders from losing everything they've fought for.